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Ulfix Sugar Free Oral Suspension 200ml
Ulfix is indicated for adults and adolescents (14 years and older) in the treatment of:
- Duodenal ulcer
- Gastric ulcer
- Chronic gastritis
- Prophylaxis of gastrointestinal hemorrhage from stress ulceration in critically ill patients
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✅ Description:
Sucralfate is a non-systemic drug that is minimally absorbed in the gastrointestinal tract. The small amount absorbed is primarily excreted in urine. Sucralfate promotes ulcer healing by forming a protective barrier over ulcer sites, inhibiting pepsin and bile action to prevent further damage.
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✔️ Dosage & Administration of Ulfix Sugar Free Oral Suspension
For Duodenal ulcer, Gastric ulcer, and Chronic gastritis:
Adults:
- 2 g twice daily (morning and bedtime) OR
- 1 g four times daily (1 hour before meals and at bedtime)
Maximum daily dose: 8 g
Treatment may last up to 12 weeks in resistant cases.
Pediatric Use:
- Not recommended for children under 14 years due to a lack of safety data.
Elderly Patients:
- No specific dosage adjustments are required, but the lowest effective dose should be used.
For Prophylaxis of Stress Ulceration (Gastrointestinal Hemorrhage):
Adults: 1 g orally or via a nasogastric tube 4 to 6 times daily.
- If administered through a nasogastric tube, flush with 10 ml water after each dose to prevent clogging.
- Treatment should not exceed 14 days unless necessary.
Administration Notes:
- Take on an empty stomach (at least 1 hour before meals).
- Avoid antacids within 30 minutes of taking Ulfix.
✔️ Side Effects of Ulfix Sugar Free Oral Suspension
- Headache (3.4%)
- Nausea (2.3%)
- Abdominal pain (2.3%)
- Constipation (1.1%)
- Diarrhea (1.1%)
- Urticaria (1.1%)
Bezoar formation (mostly in critically ill patients with delayed gastric emptying or enteral feeding).
Hyperglycemia in diabetic patients.
✔️ Overdose Effects
- Symptoms: Generally mild, including abdominal pain, nausea, vomiting.
- Animal studies: No lethal dose found, suggesting minimal risk.
✔️ Ulfix may reduce the bioavailability of certain medications, including:
- Fluoroquinolones (Ciprofloxacin, Norfloxacin), Tetracycline, Ketoconazole
- Digoxin, Warfarin, Phenytoin, Theophylline, Levothyroxine, Quinidine, H2 antagonists
- Sulpiride
Recommendations:
- Separate Ulfix and these drugs by at least 2 hours to prevent reduced absorption.
- Avoid co-administration with citrate preparations, as this can increase blood aluminum levels.
- Separate enteral feeding and Ulfix administration by 1 hour to prevent bezoar formation.
✔️ Contraindications
Hypersensitivity to Sucralfate.
✔️ Use in Pregnancy & Lactation
- Pregnancy: Safety is not established. Use only if necessary.
- Lactation: Unknown if excreted in breast milk; use with caution.
✔️ Precautions & Warnings
- Use with caution in renal impairment due to the risk of aluminum accumulation, which may cause:
- Osteodystrophy, osteomalacia, encephalopathy, and anemia.
- Regular monitoring of aluminium, phosphate, calcium, and alkaline phosphatase is recommended.
- Not recommended for dialysis patients due to aluminium toxicity risk.
- Bezoar formation risk in severely ill patients (e.g., ICU, post-surgery, or those on enteral feeding).
- Driving & Machinery Use: Avoid if experiencing dizziness or drowsiness.
✔️ Storage:
Store at a temperature not exceeding 30°C in a dry place. Protect from moisture.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
